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The HLA Gene and How It’s Affecting 25% of Us

The HLA Gene

Proteins are the building blocks for everything in your body. Bones and teeth, hair and earlobes, muscles and blood, are all made up of proteins. Those proteins help our bodies grow, work properly, and stay healthy. As well as determining characteristics such as eye and hair colour, genes can also directly cause the risk of developing a wide range of medical conditions.

Up until now, it’s been set up that generally 25% of the population is a carrier (and sufferer) of the HLA-DR gene. That is more than 80 million individuals in the United States. Hereditary investigations on specific populations  currently propose that the genuine number could be anywhere in the range of 40% and 60% around the world!

Carriers of the HLA-DR (human leukocyte antigen) gene are prone to develop chronic health issues involving systemic inflammation, whether the cause is mold, Lyme disease/ other tick borne illnesses , gluten, or countless other catalysts. HLA-DR makes a person helpless against biotoxin sickness, it additionally makes detoxification very difficult .

If you happen to have the dreaded moldy genes, there will be an increased response from your innate immune system when it identifies molds or mycotoxins. The innate immune system is the initial defense from injury and infection. The innate system fires rapid inflammatory responses to foriegn invaders. The vast majority of those experiencing Chronic Inflammatory Response Syndrome (CIRS) have the HLA DR/DQ genetic mutation. In these cases, the adaptive immune system is unable to work properly. The adaptive immune system clones receptors to bind to antigen presenting cells. This basically is the defense against extracellular microbes and their toxins, like mycotoxins. This leaves your body stuck fighting mold and mycotoxins with solely it’s innate immune system.

Symptoms can vary from person to person however, these are of the most most common toxic mold symptoms:

  • Extreme fatigue
  • Brain fog
  • Memory problems
  • Mood swings
  • Depression
  • Difficulty concentrating
  • Weakness
  • Muscle aches
  • Light sensitivity
  • Chronic cough
  • Sinus issues
  • Vertigo
  • Metallic taste in the mouth
  • Static shocks
  • Sugar cravings
  • Inability to regulate temperature
  • Digestive issues
  • Excessive thirst and frequent urination
  • Headaches

In addition to chronic inflammatory response syndrome (CIRS), mycotoxin exposure has been connected with chronic fatigue and other illnesses including allergies, asthma, mast activation cell syndrome, mitochondrial disease, pulmonary diseases, and certain rhinosinusitis.

Dr. Ritchie Shoemaker, found there are several different HLA types in humans that make some more susceptible to biotoxins than others.  The being said, a toxin is a toxin, it only takes a small amount to cause an immune response or disease. No one is immune from the effects of a toxin.  It is just that some can become sicker quicker with a smaller amount.

To find out if you are a carrier with the HLA – DR gene there’s a blood test one can get called  HLA DR typing. The word “antigen” shows up both in Human Leukocyte ANTIGEN and in the definition of toxin.  In very simple terms, an antigen is a molecule which can produce an immunologic response in the body. So HLA, are sets of genes having something to do with human immune responses and biotoxins are living organisms that cause having an immune response when present at low concentrations in the body.

Mold-Illness is a real health problem. If any of the symptoms listed above sound familiar talk to your doctor and get tested. While taking preventative measures to reduce potential exposure can be effective, it’s so important to be in touch with your surroundings, and link your environment with your health. If you’re unsure of the safety of your environment please connect us today for more information.

The information contained on this site is for informational and educational purposes only. It does not represent a health diagnosis, therapeutic recommendation or prescription for treatment. We urge you to consult and obtain medical advice from a licensed, trained, and competent medical provider for concerns with health issues.



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